Tyrone,
All the input sensitivity setting is really for is to balance the gain chain, it is not a volume control. If your mixer reaches unity gain at 1.4volts and the amps reach unity at 1.0 volt then the sensitivity can be reduced to match those levels. Amps from the same or different makers cover a wide range of input voltages from .75 up to 2.25. Mixers also have many different unity points some at 1.0 some as high as 2.0, some mixers have adjustable output gains. But with a little work on the gain chain every piece of gear can be setup to hit unity at the same point.
In the not to distant past an amp would produce a large thump when turned off many you could avoid this thump by turning down the gains before cutting power. Now the vast majority of amps (including powered speakers) have a soft turn on and off so even the thump is not an issue. A bigger issue with thump is people who don't turn their systems on or off in the proper sequence.