Taja,
I am an EV equipment guy, just like Loneavenger above. First off you have great speakers, don't cheat them with cheap amps or no DSP!
You have a lot of options, but it would be easier to answer this question if we had a budget. I have EV ZX and TX speakers 20 of them. I also have CP4000 and Q1212 amps. The cheapest way to run them (if weight is not an issue is Q1212, weighs 39 lbs), is to bridge a Q1212 per bass cab and run a pair/four of tops off a Q1212 or your XTI4000. I have four Q1212 amps in one rolling case and they will play a large gym or convention center easily. You will get a couple more db out of the CP4000 and a loss of 20 lbs, but you can buy two Q1212 amps for what you can get one CP4000 for. If money is no option then buy five CP4000s amps and don't look back.
I would warn against trying to run your bass cabs in a 2 ohm load. I have tried it, and to be honest with you, my stuff sounds the best at an 8 ohm load, with very little noticeable difference at 4 ohms. When you get to 2 ohms the power draw and heat produced by the amps is tremendous and the dampening factor pretty much disappears (the bass goes boomy instead of staying tight and solid).
You can run all four of your ZX5's off the XTI4000 amp, process them at 80-100hz up to around 18.5khz. Run the subs from 35-40hz (according to what type music you play) up to the tops crossover point. If you did this you could buy one Q1212 amp per sub cabinet and bridge them.
If you are worried about the difference in the Q1212 an CP4000, the Q1212 has a 14 lb conventional power supply and the CP4000 has a 1 lb switch mode power supply. They both have a class H output supply. The Q1212 with the conventional power supply sounds better to me, even though it cost half of what the CP4000 cost. The Q1212 is made in China, but it looks like EV has there own QC in the factory, as it is very nice inside and out. The CP4000 is made in Germany, and looks to be very well manufactured. The Q1212 actually has a better signal to noise ratio.
Good luck and I hope this helps! I love my EV equipment!!!
Ray J.